Myopic Choroidal Nevo-vascularization (CNV)
Prospective, Multi-center Trial of ranibizumab in Choroidal Neovascularization due to Pathological Myopia (REPAIR), 2013 ⏩
n=65, 12m
Study question: Ranibizumab for Myopic CNV. Study results: Tx patients gained 14 letters, greatest improvement during first month. Re-treatment rates 0 (21.5%), 1 (18.5%), 2 (16.9%), and 3 (15.4%).
Randomized controlled study of ranibizumab in patients with choroidal neovascularization secondary to pathologic myopia (RADIACE), 2014 ⏩
n=277, 12m
Study Question: Ranibizumab *2 then PRN by VA vs Ranibizumab *1 then PRN by activity vs PDT.
Study Results: Both Ranibizumab groups were similar and both better than PDT: +13.8 (group I), +14.4 (group II), and +9.3 ETDRS letters (group III).
Intravitreal Aflibercept Injection in Patients with Myopic Choroidal Neovascularization (MYRROR Study), 2015 ⏩
n=122, 44w
Study question: Aflibercept vs sham for myopic CNV. Study Results: Aflibercept gained 12.1 letters, sham lost 2. Median injections 2 by week 8. Sham switched to tx at 24w with improvement inferior to the patients treated early.
Abbreviations used on this page:
CNV - Choroidal neo-vascularization
ETDRS - Early treatment diabetic retinopathy study
PDT - Photodynamic therapy
PRN - Pro re nata, monthly follow-up and treat as needed
Tx - Treatment
VA - Visual acuity
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🚧 This is just the beginning, we are still improving this page. If you have any remarks or suggestions, please don't hesitate to contact us using the form at the bottom of the page.
n=65, 12m
Study question: Ranibizumab for Myopic CNV. Study results: Tx patients gained 14 letters, greatest improvement during first month. Re-treatment rates 0 (21.5%), 1 (18.5%), 2 (16.9%), and 3 (15.4%).
Randomized controlled study of ranibizumab in patients with choroidal neovascularization secondary to pathologic myopia (RADIACE), 2014 ⏩
n=277, 12m
Study Question: Ranibizumab *2 then PRN by VA vs Ranibizumab *1 then PRN by activity vs PDT.
Study Results: Both Ranibizumab groups were similar and both better than PDT: +13.8 (group I), +14.4 (group II), and +9.3 ETDRS letters (group III).
Intravitreal Aflibercept Injection in Patients with Myopic Choroidal Neovascularization (MYRROR Study), 2015 ⏩
n=122, 44w
Study question: Aflibercept vs sham for myopic CNV. Study Results: Aflibercept gained 12.1 letters, sham lost 2. Median injections 2 by week 8. Sham switched to tx at 24w with improvement inferior to the patients treated early.
Abbreviations used on this page:
CNV - Choroidal neo-vascularization
ETDRS - Early treatment diabetic retinopathy study
PDT - Photodynamic therapy
PRN - Pro re nata, monthly follow-up and treat as needed
Tx - Treatment
VA - Visual acuity
--------------------
🚧 This is just the beginning, we are still improving this page. If you have any remarks or suggestions, please don't hesitate to contact us using the form at the bottom of the page.
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